Synergistic catalysis: highly diastereoselective benzoxazole addition to Morita–Baylis–Hillman carbonates
نویسندگان
چکیده
منابع مشابه
Carbamoyl anion addition to N-sulfinyl imines: highly diastereoselective synthesis of α-amino amides.
Carbamoyl anions, generated from N,N-disubstituted formamides and lithium diisopropylamide, add with high diastereoselectivity to chiral N-sulfinyl aldimines and ketimines to provide α-amino amides. The methodology enables the direct introduction of a carbonyl group without the requirement of unmasking steps as with other nucleophiles. The products may be converted to α-amino esters or 1,2-diam...
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ژورنال
عنوان ژورنال: Chem. Commun.
سال: 2014
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c4cc00728j